Darksiders does a superb job of portraying a world a century after the apocalypse filled with modern cities turned to ruin, walking dead and demons of Hell. Major characters like War (your character), Samael, a demon that wants to help you on your journey and The Watcher (War's equivalent to Link's Navi) all look great, and what's better is that they all sound awesome to boot.
War is voiced by Liam O'Brien (best known as Gaara from Naruto), whose husky deep voice just sounds perfect, while The Watcher is none other than Mark Hamil, who uses a Joker-like voice to direct War in a much better way than the constant high-pitched "Hey" that followed Link around. The game's background music also boosts the feel of the game with an epic-feeling soundtrack.